Professor David Goldblatt is a Consultant Paediatric Immunologist at Great Ormond Street Hospital (GOSH) and Professor of Vaccionology and Immunology and Head of the Immunobiology Unit at the University College London (UCL) Great Ormond Street Institute of Child Health.
He is also the Director of Clinical Research and Development at GOSH and the Director of the National Institute for Health Research (NIHR) Biomedical Research Centre at GOSH/UCL. He is a regular advisor to the World Health Organisation (WHO) on bacterial conjugate vaccines and is Director of the WHO Reference Laboratory for Pneumococcal Serology based at the UCL Great Ormond Street Institute of Child Health.
• Chronic granulomatous disease
• Qualified from the University of Cape Town, South Africa
• MB ChB
• PhD in immunology from University of London, United Kingdom
• Regular advisor to the World Health Organisation (WHO) on bacterial conjugate vaccines
• Director of the WHO Reference Laboratory for Pneumococcal Serology based at the UCL Institute of Child Health in London
• Director of Clinical Research and Development at GOSH
• Director of the National Institute for Health Research (NIHR) Biomedical Research Centre at GOSH/UCL
• Member of the United Kingdom Department of Health Joint Committee on Vaccines and Immunisation (JCVI) for 10 years. Contributes to two JCVI subcommittees
• Served as a member of both the Medical Research Council and Wellcome Trust funding panels
• Member of the Wellcome Trust’s 'Immune System in Health and Disease' Expert Review Group
Professor Goldblatt is a Professor of Vaccinology and Immunology and Head of the Immunobiology Unit at the ICH. He has a long-standing interest in the immune response to vaccines and infectious diseases in childhood and has an active research programme studying bacterial conjugate vaccines, the kinetics of immunological memory and immunity and infections in early life.
He is involved in clinical trials and basic science research projects in the United Kingdom, Africa and south-east Asia and collaborates with colleagues in Europe and the USA.
News & Publications
Moens, L., Verbinnen, B., Covens, K., Wuyts, G., Johnson, M., Roalfe, L., . . . Bossuyt, X. 2015. Anti-pneumococcal capsular polysaccharide antibody response and CD5 B lymphocyte subsets. Infection and immunity.
Kantsø, B., Green, N., Goldblatt, D., & Benfield, T. 2015. Antibody response is more likely to pneumococcal proteins than to polysaccharide after HIV-associated invasive pneumococcal disease. The Journal of infectious diseases.
Numminen, E., Chewapreecha, C., Turner, C., Goldblatt, D., Nosten, F., Bentley, S. D., . . . Corander, J. 2015. Climate induces seasonality in pneumococcal transmission. Scientific reports. 5, pp. 11344-?.
van Tonder, A. J., Bray, J. E., Roalfe, L., White, R., Zancolli, M., Quirk, S. J., . . . Brueggemann, A. B. 2015. Genomics reveals the worldwide distribution of multidrug-resistant serotype 6E pneumococci. Journal of clinical microbiology.
Ladhani, S. N., Andrews, N. J., Waight, P., Hallis, B., Matheson, M., England, A., . . . Miller, E. 2015. Interchangeability of meningococcal group C conjugate vaccines with different carrier proteins in the United Kingdom infant immunisation schedule. Vaccine. 33 (5) pp. 648-655.
Grant, L., Burbidge, P., Haston, M., Johnson, M., Reid, R., Santosham, M., . . . O Brien, K. L. 2015. Persistence of IgG Antibody Following Routine Infant Immunization with the 7-Valent Pneumococcal Conjugate Vaccine. Pediatric Infectious Disease Journal.
Blumental, S., Roalfe, L., Zancolli, M., Johnson, M., Burbidge, P., Goldblatt, D., . . . Mueller, J. E. 2015. Streptococcus pneumoniae serotype 1 burden in the African meningitis belt: Exploration of functionality in specific antibodies. Clinical and Vaccine Immunology. 22 (4) pp. 404-412.
De Waroux, O. L., Flasche, S., Prieto-Merino, D., Goldblatt, D., & Edmunds, W. J. 2015. The Efficacy and Duration of Protection of Pneumococcal Conjugate Vaccines Against Nasopharyngeal Carriage: A Meta-Regression Model. The Pediatric infectious disease journal.
Bamford, A., Kampmann, B., Hart, M., Kelleher, P., Lyall, H., & Goldblatt, D. 2015. The influence of paediatric HIV infection on circulating B cell subsets and CXCR5+ T helper cells. Clinical and Experimental Immunology. 181 (1) pp. 110-117.
Flasche, S., Van Hoek, A. J., Goldblatt, D., Edmunds, W. J., O'Brien, K. L., Scott, J. A., & Miller, E. 2015. The Potential for Reducing the Number of Pneumococcal Conjugate Vaccine Doses While Sustaining Herd Immunity in High-Income Countries. PLoS medicine. 12 (6) p. e1001839-?
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