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New funding to support pioneering thymus transplant research at GOSH
Professors Graham Davies and Adrian Thrasher have been awarded funding from Great Ormond Street Hospital (GOSH) Charity to further develop a cutting-edge new treatment for children with the rare immunodeficiency condition complete DiGeorge syndrome (cDGS).
The new research project will build on a previous trial led by Professor Davies which showed that transplant of donor thymus tissue restored T-cell numbers in 75 percent of patients with cDGS. Patients developed the ability to fight common infections and should have a much longer life expectancy. The new research will allow researchers to look at how to maximise the number of T-cells produced after thymus tissue is transplanted into children with cDGS.
The research is support by GOSH charity. This new award builds on earlier work supported by the National Institute for Health Research (NIHR) GOSH Biomedical Research Centre (BRC), EU FP7, GOSH Charity, Mason Medical Research and the Wellcome Trust.
The new research project will build on a previous trial led by Professor Davies which showed that transplant of donor thymus tissue restored T-cell numbers in 75 percent of patients with cDGS. Patients developed the ability to fight common infections and should have a much longer life expectancy. The new research will allow researchers to look at how to maximise the number of T-cells produced after thymus tissue is transplanted into children with cDGS.
The research is support by GOSH charity. This new award builds on earlier work supported by the National Institute for Health Research (NIHR) GOSH Biomedical Research Centre (BRC), EU FP7, GOSH Charity, Mason Medical Research and the Wellcome Trust.
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